|
|
L-3-hydroxykynurenine + 2-oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
| |
KEGG:
R04171
MetaCyc:
RXN-10721
SABIO-RK:
12045
|
|
|
|
L-kynurenine + H2O <=> H+ + L-alanine + anthranilate
|
3.7.1.3
kynureninase
|
–
|
| |
BRENDA:
BR29549
KEGG:
R00987
MetaCyc:
KYNURENINASE-RXN
SABIO-RK:
1281
|
|
|
|
L-kynurenine + O2 + NADPH + H+ <=> L-3-hydroxykynurenine + H2O + NADP+
|
1.14.13.9
kynurenine 3-monooxygenase
|
–
|
| |
BRENDA:
BR33724;
BS386517
KEGG:
R01960
MetaCyc:
KYNURENINE-3-MONOOXYGENASE-RXN
SABIO-RK:
2007
|
|
|
|
3-Hydroxyanthranilate + O2 <=> alpha-amino-beta-carboxymuconate-epsilon-semialdehyde
|
1.13.11.6
3-hydroxyanthranilate 3,4-dioxygenase
|
–
|
| |
BRENDA:
BR40468
KEGG:
R02665
MetaCyc:
1.13.11.6-RXN
SABIO-RK:
2561
|
|
|
|
L-tryptophan + O2 <=> N-formyl-L-kynurenine
|
1.13.11.11
tryptophan 2,3-dioxygenase
1.13.11.26
peptide-tryptophan 2,3-dioxygenase
1.13.11.52
indoleamine 2,3-dioxygenase
|
–
–
–
|
| |
BRENDA:
BR37070;
BS380639
KEGG:
R00678
MetaCyc:
RXN-8665
SABIO-RK:
1060
|
|
|
|
L-3-hydroxykynurenine + H2O <=> H+ + 3-Hydroxyanthranilate + L-alanine
|
3.7.1.3
kynureninase
|
–
|
| |
BRENDA:
BS190196
KEGG:
R02668
MetaCyc:
3-HYDROXY-KYNURENINASE-RXN
SABIO-RK:
12038;
2564
|
|
|
|
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate <=> H+ + xanthurenic_acid + H2O
|
not assigned
|
–
|
| |
KEGG:
R03954
MetaCyc:
RXN-10722
|
|
|
|
N-formyl-L-kynurenine + H2O <=> L-kynurenine + formate + H+
|
3.5.1.9
arylformamidase
|
–
|
| |
BRENDA:
BR22715
KEGG:
R01959
MetaCyc:
ARYLFORMAMIDASE-RXN
SABIO-RK:
2006
|
|
|
|
2-aminomuconate_6-semialdehyde <=> Picolinic_acid + H2O + H+
|
not assigned
|
–
|
| |
KEGG:
R11022
MetaCyc:
RXN-10723
|
|
|
|
L-kynurenine + 2-oxoglutarate <=> L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.75
cysteine-conjugate transaminase
|
–
–
|
| |
BRENDA:
BR47389
KEGG:
R01956
MetaCyc:
2.6.1.7-RXN
SABIO-RK:
2003
|
|
|
|
4-(2-aminophenyl)-2,4-dioxobutanoate <=> Kynurenic_acid + H2O + H+
|
0.0.0.0
|
–
|
| |
BRENDA:
BR52896
KEGG:
R03445
MetaCyc:
RXN-10720
|
|
